Vol. 1 No. 11 (2021)
Health Technology Reviews

Nabilone for the Treatment of Post-Traumatic Stress Disorder: A 2021 Update

Published November 22, 2021

Key Messages

  • Two systematic reviews that met the inclusion criteria of this report were identified. Within these reviews, the clinical effectiveness of nabilone for the treatment of adult patients with post-traumatic stress disorder (PTSD) was evaluated in 1 relevant primary study. This single-arm, open-label study found that most patients with PTSD experienced total cessation or reduction of nightmares following treatment with nabilone. This study lacked a control group, limiting the certainty of these findings.
  • No evidence-based guidelines regarding the use of nabilone for the treatment of adult patients with PTSD were identified.