Vol. 2 No. 12 (2022)
Reimbursement Reviews

Abemaciclib (Verzenio)

Published December 23, 2022

Key Messages

  • CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
  • The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
  • This review assesses abemaciclib (Verzenio), 50 mg, 100 mg, 150 mg, 200 mg oral tablet.
  • Indication: In combination with endocrine therapy for the adjuvant treatment of adult patients with HR-positive, HER2-negative, node-positive early breast cancer at high risk of disease recurrence based on clinicopathologic features and a Ki-67 test score ≥ 20%.