Vol. 2 No. 4 (2022)
Health Technology Reviews

Systemic Thrombolysis and Endovascular Therapy for Large Vessel Occlusion Acute Ischemic Stroke

Published April 19, 2022

Key Messages

Evidence was mixed, with higher-quality evidence suggesting that there were no differences between treatment with alteplase before endovascular therapy or endovascular therapy alone in patients with large vessel occlusion acute ischemic stroke for outcomes related to safety and efficacy, and lower-quality evidence indicating a difference between the groups for certain outcomes.